Madeleine Will has been an advocate for persons with disabilities for three decades. She has led efforts to establish services nationally for infants and toddlers with disabilities and their families. In addition, she has promoted the concept of inclusive general education classrooms for students with disabilities and helped and to create transition and supported employment programs.

In 2004, Ms. Will was named Director of the National Policy Center of the National Down Syndrome Society. The National Down Syndrome Society, a disability organization made up of 190 affiliates across the country, seeks to improve the quality of life for persons with Down syndrome through efforts in education, research and advocacy.